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New weight loss drug: FDA approves Zepbound, a version of diabetes drug Mounjaro for obesity

Published Wed, 12 Mar 2025 23:23:53 GMT

By JONEL ALECCIA (AP Health Writer)A new version of the popular diabetes treatment Mounjaro can be sold as a weight-loss drug, U.S. regulators announced Wednesday.The U.S. Food and Drug Administration approved Eli Lilly’s Zepbound, or tirzepatide. The drug helped dieters lose about a quarter of their body weight, or 60 pounds (27 kilograms), in a recent study.Zepbound is the latest diabetes drug approved for weight loss, joining Novo Nordisk’s Wegovy, a high-dose version of its diabetes treatment Ozempic.The FDA approved Lilly’s drug for people who are considered obese, with a body mass index of 30 or higher, or those who are overweight with a related health condition, like high blood pressure, high cholesterol or diabetes. The drug should be paired with a healthy diet and regular exercise, the FDA said.In the U.S., at least 100 million adults and about 15 million children are considered obese.The drug tirzepatide in Zepbound and Mounjaro and semaglutide in Wegovy and Ozempic work b...

Driver survives after vehicle hit by train in Oakland

Published Wed, 12 Mar 2025 23:23:53 GMT

OAKLAND — A driver was injured Wednesday morning when his SUV was hit by an Amtrak train near Jack London Square, authorities said.His condition was not immediately available.The collision happened about 7:25 a.m. Wednesday at the intersection of Oak Street and Embarcadero West, a few blocks from Jack London Square Amtrak Station.Related ArticlesCrashes and Disasters | ‘Black Panther’ stuntman, three of his children killed in car crash in Atlanta Crashes and Disasters | San Jose reaches settlement for scooter accident that left woman with broken teeth, nose Crashes and Disasters | Tarantula sighting results in car accident in Death Valley National Park Crashes and Disasters | Hit-and-run injures 7-year-old boy trick-or-treating in Berkeley Crashes and Disasters | Truck filled with thousands of pounds of marijuana crashes into California fire station’s gates Authorities said initial reports were tha...

San Jose police arrest second teen in connection to hit-and-run that killed pregnant woman, baby

Published Wed, 12 Mar 2025 23:23:53 GMT

SAN JOSE — Police arrested a second teenager in connection to the Oct. 24 crash in San Jose that killed a woman who was 27 weeks pregnant, as well as her baby, who was delivered after the crash but died in a hospital, according to authorities.The 15-year-old boy was arrested on Nov. 2, police announced Wednesday. Police did not identify the teen or specify any booking charges, citing laws protecting juvenile suspects and saying only that he was believed to have been inside the vehicle at the time of the deadly collision.Related ArticlesCrashes and Disasters | Nine arrested in sprawling Santa Clara County sex-trafficking ring Crashes and Disasters | Ex-San Jose Jr. Sharks coach arrested on suspicion of sexually assaulting child Crashes and Disasters | ‘Party mom’ who wouldn’t take 17 years for alleged drunken teen sex bashes could face 31 years Crashes and Disasters | Red-flag laws for disarming troubled peo...

Four-bedroom home in Saratoga sells for $3.7 million

Published Wed, 12 Mar 2025 23:23:53 GMT

12625 Cheverly Court – Google Street ViewThe spacious property located in the 12600 block of Cheverly Court in Saratoga was sold on Oct. 25, 2023. The $3,650,000 purchase price works out to $1,497 per square foot. The house, built in 1967, has an interior space of 2,438 square feet. This single-story house presents a roomy floor plan, featuring four bedrooms and three baths. Inside, there is a fireplace. Additionally, the home is equipped with a two-car garage, accommodating vehicles and storage needs efficiently. The property’s backyard is further enhanced by both a spa and a pool.Additional houses that have recently been sold close by include:In July 2023, a 2,495-square-foot home on Ione Court in Saratoga sold for $3,700,000, a price per square foot of $1,483. The home has 4 bedrooms and 3 bathrooms.A 2,235-square-foot home on the 12600 block of Lido Way in Saratoga sold in June 2023, for $3,063,000, a price per square foot of $1,370. The home has 4 bedrooms and 4 bathrooms.On Pi...

Kurtenbach: The 49ers’ big second-half question — where’s the juice?

Published Wed, 12 Mar 2025 23:23:53 GMT

So much has gone wrong for the 49ers’ defense over the last few weeks, it’s difficult to know where to start making corrections.They need to rev up the pass rush — the acquisition of Chase Young is aimed at doing that. They need to stop calling such plain and predictable plays, which could be helped by film study over the bye.But perhaps this defense’s biggest issue heading into the second half of the season is that it has lost its swagger.And I don’t think defensive coordinator Steve Wilks moving from the coaches’ booth to the sideline is going to help with this.A little film study of my own shows a defense that is devoid of juice.The Niners’ defensive personnel is arguably better than last season. And yet they look to be a shell of that former team.Like a balloon without air, this Niners’ defense looks limp.Someone needs to pump them up.The NFL is a billion-dollar business with innovative coaches, but it’s still a simple game i...

San Jose Sharks acquire defenseman from Minnesota Wild

Published Wed, 12 Mar 2025 23:23:53 GMT

SAN JOSE – The San Jose Sharks acquired defenseman Calen Addison from the Minnesota Wild on Wednesday for AHL winger Adam Raska and a 2026 fifth-round draft pick.Addison, 23, had five assists in 12 games for the Wild this season and has five goals and 38 points in 92 career NHL games, all with Minnesota. A second-round draft pick of the Pittsburgh Penguins in 2018, Addison was averaging just under 17 minutes of ice time per game this season.Addison would give the Sharks more of a true quarterback on the man advantage as he had been, up until recently, on Minnesota’s top power-play unit. He was third on the Wild this season in overall power play time on ice, averaging 4:12 per game.The Sharks went 1-for-5 on the power play in their 2-1 victory over the Philadelphia Flyers on Tuesday, with William Eklund’s second-period goal on a 4-on-3 man advantage proving to be the winner.The victory was the Sharks’ first of the season after 11 straight defeats. San Jose entered W...

The end of the actors’ strike seemed within reach. Why is a SAG-AFTRA deal taking so long?

Published Wed, 12 Mar 2025 23:23:53 GMT

Christi Carras, Wendy Lee and Meg James | (TNS) Los Angeles TimesAbout this time last week, the major Hollywood studios were optimistic and the performers union SAG-AFTRA was cautiously optimistic that a tentative deal to end the actors’ strike was within reach.One hundred and seventeen days into the walkout that has ground the entertainment industry to a near-halt, such a settlement remains to be seen. On Monday afternoon, the Screen Actors Guild-American Federation of Television and Radio Artists said in a statement that there still were “several essential items” the sides had yet to agree on.This came after the union formally responded to what the Alliance of Motion Picture and Television Producers described as its “last, best and final offer,” the contents of which are starting to emerge through anonymous sources. The parties have been going back and forth for about two weeks of frequent meetings in an effort to resolve their labor dispute.Despite signs of progress, a deal betwe...

Dorsey's Block, formerly Square, to slash 1,000 jobs

Published Wed, 12 Mar 2025 23:23:53 GMT

SAN FRANCISCO (KRON) -- Block, the financial services tech company run by Twitter founder Jack Dorsey, plans to cut around 1,000 jobs in the latest round of layoffs to roil the Bay Area tech industry. In a third-quarter shareholder letter published last Thursday, Dorsey, announced the company would be capping its employee head count at 12,000.Block currently employs just over 13,000 people, according to the transcript of last week's earnings call, posted on Seeking Alpha. The proposed job cuts would amount to roughly 1,000 workers losing their jobs. Nextdoor to lay off 25% of its staff as part of cost reduction plan The job cuts are expected to be implemented over several months with the company targeting the end of 2024 to reach its goal, according to the earnings call transcript."As we continue to view the business through the lens of our investment framework, we continue to find opportunities for constraints we believe will lead to greater growth," said Dorsey in the sharehold...

FRP Holdings: Q3 Earnings Snapshot

Published Wed, 12 Mar 2025 23:23:53 GMT

JACKSONVILLE, Fla. (AP) — JACKSONVILLE, Fla. (AP) — FRP Holdings Inc. (FRPH) on Wednesday reported net income of $1.3 million in its third quarter.On a per-share basis, the Jacksonville, Florida-based company said it had profit of 13 cents.The real estate company posted revenue of $10.6 million in the period._____This story was generated by Automated Insights (http://automatedinsights.com/ap) using data from Zacks Investment Research. Access a Zacks stock report on FRPH at https://www.zacks.com/ap/FRPHSource

King Charles proposes bill that takes aim at European Super League

Published Wed, 12 Mar 2025 23:23:53 GMT

MANCHESTER, England (AP) — Over two fraught days in April 2021, a newly formed “Super League” threatened to change the face of European soccer by creating an elite tournament that would protect 15 top clubs from relegation.It quickly collapsed, but a U.K. government bill announced by King Charles on Tuesday proposes powers to block English teams from attempting to join a breakaway league in the future.In a document explaining the new Football Governance Bill, the government said the European Super League was “fundamentally uncompetitive” and “threatened to undermine the footballing pyramid against the wishes of fans.”“Fans will no longer face the prospect of seeing their clubs sign up to ill-thought out proposals such as the European Super League,” the document said.Manchester United, Manchester City, Liverpool, Arsenal, Chelsea and Tottenham were among 12 rebel clubs from England, Spain and Italy that planned to be part of the breakaway league. Real Madrid, Barcelona, A...